Episode 95 - Dr. Sarah Daccarett - Autoimmunity in Women: Is It Really a Hormone Problem?

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Meet Dr. Sarah Daccarett

Dr. Sarah Daccarett, MD, is a longevity and hormone specialist and the Founder and CEO of Inner Balance, a women’s health company dedicated to expanding access to evidence-based hormone care. Her work focuses on modern hormone treatment, telemedicine-driven care models, and closing long-standing gaps in women’s health through science, education, and patient-centered practice.


What We Talk About

  • Why 80% of autoimmune diseases affect women and how the female immune system is hormonally driven.

  • How puberty, pregnancy, postpartum, and perimenopause trigger autoimmune flares and what that reveals about hormone immune regulation.

  • Why pregnancy can improve conditions like lupus and celiac, showing autoimmunity is hormonally influenced.

  • The link between estrogen, mitochondrial health, and immune burnout, and how low estrogen drives inflammation.

  • How immune dysfunction shows up as food sensitivities, eczema, infections, hives, or bloating.

  • The hormone gut connection, including how estrogen and progesterone affect gut barrier integrity and SIBO risk.

  • Why treating leaky gut may fail if hormone deficiencies are not addressed.

  • The roles of progesterone, estrogen, testosterone, and DHEA, and why ratios matter more than isolated lab numbers.

  • Why perimenopause can begin in a woman’s 20s or 30s and contribute to autoimmunity.

  • What to expect with bioidentical hormone therapy, including timelines for symptom improvement.


Episode Resources

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Keywords

hormones, autoimmunity, female immune system, estrogen, immune health, progesterone balance, perimenopause, hormone gut connection, mitochondrial dysfunction, bioidentical hormone therapy, immune aging, chronic inflammation in women, hormone optimization for longevity