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Episode 70 - Dr. Mary Pardee - Perimenopause 101: What’s Really Happening to Your Hormones

Episode 70 - Dr. Mary Pardee - Perimenopause 101: What’s Really Happening to Your Hormones

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Episode 70 - Dr. Mary Pardee - Perimenopause 101: What’s Really Happening to Your Hormones

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Meet Dr. Mary Pardee

Dr. Mary Pardee is a Naturopathic Medical Doctor specializing in preventative medicine and longevity, based in Los Angeles, California. With an undergraduate degree in human nutrition and experience in exercise physiology and performance research with the US government, she brings a comprehensive approach to health. Dr. Mary holds a doctorate in naturopathic medicine from Bastyr University and is the founder of modern med, a practice offering both in-person and telemedicine consultations. Her primary focus is bridging the healthspan-lifespan gap, helping patients live longer, healthier, and more vibrant lives. She is licensed in California and Colorado.

What We Talk About

• Dr. Mary Pardee’s unique approach to functional and integrative medicine, and why she focuses on gut-brain-hormone interactions to support women through perimenopause and menopause.
• The most common hormone imbalances in women over 35, including low progesterone, estrogen dominance, and sluggish thyroid and how they impact sleep, metabolism, and emotional health.
• Why symptoms like fatigue, bloating, mood swings, irregular cycles, and night sweats are often brushed off or misdiagnosed in conventional care.
• How to use at-home hormone testing and functional labs to get a real picture of where your body stands without relying on outdated bloodwork alone.
• The critical role of gut health in hormone balance, including how estrogen is processed through the microbiome and what gut inflammation does to cortisol and insulin.
• Why perimenopause is often a bigger hormonal rollercoaster than menopause, and how stress, nutrient deficiencies, and environmental toxins amplify the chaos.
• Dr. Pardee’s view on bioidentical hormone therapy, who it helps, how to use it wisely, and when lifestyle change may be enough.
• The importance of supporting mitochondrial function, adrenal recovery, and blood sugar stability to reduce perimenopausal symptoms.
• Her go-to tools for nervous system regulation, including breathwork, vagus nerve stimulation, and why overstimulating workouts can make things worse.
• The connection between hormone health, trauma, and the gut-brain axis and how healing must happen on all three levels to see true results.
• Dr. Pardee’s practical advice for women who feel dismissed or overwhelmed: where to start, what to test, and how to build a hormone-supportive lifestyle that actually lasts.

Episode Resources

Function Health
Lab testing for 100+ biomarkers including hormones, thyroid, inflammation, and nutrients. Use code ESCHLICK10 for a discount.
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ButcherBox
High-quality meats delivered to your door to support stable blood sugar, lean muscle, and hormone health.
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Bonafide Provisions
Organic bone broth rich in collagen, minerals, and amino acids to support gut and hormone health. Use code TRAILTOHEALTH for 15% off.
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Tethos
Non-alcoholic wine alternatives that support liver health and hormonal balance. Use code TRAILTOHEALTH for 10% off.
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BodyBio
Phospholipids, butyrate, and minerals to support mood, metabolism, and mitochondria during hormonal shifts. Use code TRAILTOHEALTH for 15% off.
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Rho Nutrition
Targeted supplements for hormone health, energy, and blood sugar support. Use code TRAILTOHEALTH for 15% off your first order.
https://shop.thetrailtohealth.com/Rho

Promix
Clean protein and functional supplements for strength, recovery, and hormone support. Use code THETRAILTOHEALTH for 10% off.
https://shop.thetrailtohealth.com/Promix

Pulsetto
Wearable vagus nerve stimulator to calm your nervous system and improve sleep.
https://shop.thetrailtohealth.com/Pulsetto

Earthing
Grounding tools to reduce inflammation, regulate cortisol, and support hormone balance.
https://shop.thetrailtohealth.com/Earthing

Keywords

Hormone health, perimenopause, balanced hormones, gut brain connection, midlife health, menopause relief, root cause healing, functional medicine, hormone balance, cycle support, adrenal health, hormone reset, perimenopause health, women wellness, midlife women, inflammation relief, biohacking women, functional health, natural hormones